FIS1 CLIA Kit for Human(Homo sapiens) | EIAab.comFIS1 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > FIS1(Gene name) > Human

FIS1 (Gene name),

Mitochondrial fission 1 protein (Protein name ), FIS1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FIS1(CGI-135;TTC11);

Protein name:

Mitochondrial fission 1 protein;

Alternative:

Tetratricopeptide repeat protein 11(TPR repeat protein 11);FIS1 homolog(hFis1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with DNM1L/DLP1 through the TPR region. Interacts with MARCH5. Interacts with MID51.

Function:

Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Subcellular Location:

Mitochondrion outer membrane Single-pass membrane protein Peroxisome membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

152

Sequence:

50:

100:

150:

152:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.423968

SMR:

Q9Y3D6

String:

Q9Y3D6

KEGG:

hsa:51024

Pfam:

PF14853

MIM:

609003

STRING:

9606.ENSP00000223136

Uniprot:

Q9Y3D6

FOR

ELISA Kit for Human Mitochondrial fission 1 protein

Cat.:

E13784b

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ELISA Kit for Human Mitochondrial fission 1 protein

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E13784r

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96T

ELISA Kit for Human Mitochondrial fission 1 protein

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E13784m

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96T

ELISA Kit for Human Mitochondrial fission 1 protein

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E13784h

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96T

CLIA Kit for Human Mitochondrial fission 1 protein

Cat.:

U13784m

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MSDS:

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Packing:

96T

CLIA Kit for Human Mitochondrial fission 1 protein

Cat.:

U13784h

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Packing:

96T

CLIA Kit for Human Mitochondrial fission 1 protein

Cat.:

U13784r

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96T

CLIA Kit for Human Mitochondrial fission 1 protein

Cat.:

U13784b

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96T

Polyclonal Antibody for Human Mitochondrial fission 1 protein

Cat.:

P13784Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Mitochondrial fission 1 protein

Cat.:

P13784Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Mitochondrial fission 1 protein

Cat.:

P13784Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mitochondrial fission 1 protein

Monoclonal Antibody for Human Mitochondrial fission 1 protein

Protein for Human Mitochondrial fission 1 protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold."
Dohm J.A. , Lee S.J. , Hardwick J.M. , Hill R.B. , Gittis A.G.
Proteins54:153-156(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 1-123
2.

"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
Lai C.-H. , Chou C.-Y. , Ch'ang L.-Y. , Liu C.-S. , Lin W.-C.
Genome Res.10:703-713(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
5.

Bienvenut W.V.
Submitted (2005-06) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-16;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
tissue: B-cell lymphoma.
6.

"hFis1, a novel component of the mammalian mitochondrial fission machinery."
James D.I. , Parone P.A. , Mattenberger Y. , Martinou J.-C.
J. Biol. Chem.278:36373-36379(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
7.

"The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1."
Yoon Y. , Krueger E.W. , Oswald B.J. , McNiven M.A.
Mol. Cell. Biol.23:5409-5420(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH DNM1L
8.

"Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology."
Stojanovski D. , Koutsopoulos O.S. , Okamoto K. , Ryan M.T.
J. Cell Sci.117:1201-1210(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;MUTAGENESIS OF LYS-149 AND LYS-151
9.

"Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1."
Yu T. , Fox R.J. , Burwell L.S. , Yoon Y.
J. Cell Sci.118:4141-4151(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH DNM1L;MUTAGENESIS OF LEU-14; LEU-42; LEU-58; LEU-77; LEU-91 AND LEU-110
10.

"A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells."
Koch A. , Yoon Y. , Bonekamp N.A. , McNiven M.A. , Schrader M.
Mol. Biol. Cell16:5077-5086(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
11.

"A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics."
Yonashiro R. , Ishido S. , Kyo S. , Fukuda T. , Goto E. , Matsuki Y. , Ohmura-Hoshino M. , Sada K. , Hotta H. , Yamamura H. , Inatome R. , Yanagi S.
EMBO J.25:3618-3626(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION BY MARCH5;INTERACTION WITH MARCH5
12.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission."
Zhao J. , Liu T. , Jin S. , Wang X. , Qu M. , Uhlen P. , Tomilin N. , Shupliakov O. , Lendahl U. , Nister M.
EMBO J.30:2762-2778(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MIEF1
15.

"MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission."
Palmer C.S. , Elgass K.D. , Parton R.G. , Osellame L.D. , Stojanovski D. , Ryan M.T.
J. Biol. Chem.288:27584-27593(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
16.

"Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission."
Loson O.C. , Song Z. , Chen H. , Chan D.C.
Mol. Biol. Cell24:659-667(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
17.

"Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission."
Koirala S. , Guo Q. , Kalia R. , Bui H.T. , Eckert D.M. , Frost A. , Shaw J.M.
Proc. Natl. Acad. Sci. U.S.A.110:E1342-E1351(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
18.

"The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle."
Suzuki M. , Jeong S.-Y. , Karbowski M. , Youle R.J. , Tjandra N.
J. Mol. Biol.334:445-458(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;SUBCELLULAR LOCATION

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